Smart Nutri, Choles Down - 60 Capsules

PRODUCT HIGHLIGHTS

• Reduce Total Cholesterol
• Reduce LDL
• Reduce Triglycerides
• Increase HDL
• Reduce Blood Sugar Level(diabetic) 

It is estimated that almost 1 out of every 3 people are fighting unhealthy cholesterol levels so you are not alone. Up until recently, there were only a couple of options to try and battle this. 1; focus on diet and exercise, and 2; take synthetic, pharmaceutical drugs. While diet and exercise are great helps, they are hard to stick to and sometimes not enough. With drugs, they are often harmful with unintended side effects, as well as can interact with other drugs you might be taking. Here are just some of the negative side effects from using statin drugs to attempt cholesterol control: Heart and muscle damage, memory loss, fatigue, digestive problems, blood sugar disorders, and depletion of Coenzyme Q10.But there is an alternative to statin drugs. It's an all-natural, plant-based, cholesterol supporting supplement called Citrus Bergamot. This alternative to synthetic drugs from pharmaceutical companies delivers safe, effective results without the risk of negative side effects or harmful cross-drug interactions. It truly is natures answer to high cholesterol. 

MORE INFORMATION

Ingredients:

Bergamonte Citrus BergamiaRisso: Citrus bergamiaRisso, grows in the Ionic coast of Southern Calabria Italy. Because of the weather condition, Citrus Bergamot is restricted to only grows in Calabria Italy, where it controls 80% of worldwide production. Citrus Bergamot works by blocking a key enzyme in the production of cholesterol. Cholesterol is a natural product of the liver and in the right amounts does not pose a problem to the body. The human body however, sometimes produces too much cholesterol which can lead to very serious problems. Citrus Bergamot also has the highest content of flavanoids in the citrus family of fruits. Flavanoids are plant nutrients found in flowers, rinds, leaves, and fruits. Many of those flavanoids have been shown to reduce cholesterol in clinical studies. Two flavanoids; brutelidine and melitidine, as well as the active compound naringin have been shown through research to significantly reduce the overall cholesterol, LDLs triglycerides, and blood glucose levels, while increasing HDLs (good cholesterol).

* Health Benefits of Citrus Bergamot: Cardiovascular Health, Reduce Total Cholesterol, Reduce LDL, Reduce Triglycerides, Increase HDL, Reduce blood sugar level (diabetic), Healthy Weight Loss

Ascorbic Acid: L-ascorbic acid or L-ascorbate or Vitamin C is an essential nutrient for humans and certain other animal species. Ascorbic acid is well known for its antioxidant activity, acting as a reducing agent to reverse oxidation in liquids. When there are more free radicals (reactive oxygen species, ROS) in the human body than antioxidants, the condition is called oxidative stress, and has an impact on cardiovascular disease, hypertension, chronic inflammatory diseases, and diabetes as well as on critically ill patients and individuals with severe burns. Individuals experiencing oxidative stress have ascorbate blood levels lower than 45 µmol/L, compared to healthy individual who range between 61.4-80 µmol/L.  

It is not yet certain whether vitamin C and antioxidants in general prevent oxidative stress-related diseases and promote health. Clinical studies regarding the effects of vitamin C supplementation on lipoproteins and cholesterol have found that vitamin C supplementation does not improve disease markers in the blood. Vitamin C may contribute to decreased risk of cardiovascular disease and strokes through a small reduction in systolic blood pressure, and was also found to both increase ascorbic acid levels and reduce levels of resistin serum, another likely determinant of oxidative stress and cardiovascular risk.

Human Clinical Study

->Double-blind, placebo-controlled trial

Bergamot polyphenolic fraction (BPF; 500 to 1000 mg/day for 30 days, n=238) reduces total cholesterol (tChol), LDL cholesterol (c-LDL), triglycerides (TG), and blood glucose (BG) 

Data is polled from 238 patients:

(1) 82 patients with isolated hypercholesterolemia (LDL>130)
(2) 76 patients with mixed dyslipedemia (hypercholesterolemia and hypertryglyceridemia)
(3) 48 patients with mixed hyperlipemia and glycemia)
(4) 32 patients previously on statin, 60 days wash out period 

Label

Frequently Asked Questions

Q.What is cholesterol?

A. Cholesterol is one of the body's fats (lipids). Cholesterol and another lipid, triglyceride, are important building blocks in the structure of cells and are also used in making hormones and producing energy. To some extent, the cholesterol level in blood depends on what you eat, but it is mainly dependent on how the body makes cholesterol in the liver.

Q. What can cause high cholesterol levels?

A.  Having too much cholesterol in the blood is not a disease in itself, but can lead to the hardening and narrowing of the arteries (atherosclerosis) in the major vascular systems. Cholesterol is a direct contributor to cardiovascular disease, which can lead to strokes and heart attacks.

High cholesterol is also seen in connection with other diseases such as:

• reduced metabolism due to thyroid problems
• kidney diseases
• diabetes
• alcohol abuse

Q.  What is the meaning of Cholesterol Numbers?

Cholesterol comes in several different forms, but doctors focus mostly on two: LDL cholesterol and HDL cholesterol. 

LDL is also called "bad cholesterol" -- LDL cholesterol can clog your arteries, increasing the risk of heart attack and stroke. Most people should aim for a level of less than 100 mg/dL. However, people who already have heart disease may need to aim for under 70 mg/dL.

HDL is "good cholesterol" -- This type of cholesterol attaches to bad cholesterol and brings it to the liver, where it's filtered out of the body. So HDL cholesterol reduces the amount of bad cholesterol in your system. You should aim for 60 mg/dL or higher.

Triglycerides are not cholesterol but another type of fat floating in your blood. Just as with bad cholesterol, having a high level of triglycerides increases your risk of cardiovascular problems. Aim for a fasting level of less than 150 mg/Dl

Q. How does the doctor make the diagnosis of hypercholesterolemiaor hyperlipidemia?

A. After a 12-hour fast in which only water is consumed, a blood sample is taken to determine the level of:

• LDL cholesterol
• HDL cholesterol
• triglyceride
• total cholesterol in the blood

Test levels are adjusted to take into account age, weight, diabetes, kidney diseases and decreased metabolism.
Cholesterol count also rises during pregnancy and drops significantly for at least three months after a heart attack. 

The doctor can make a rough estimate of the extent of cardiovascular disease by checking the pulse, the blood pressure, listening to the heart and large arteries, checking kidney function with a blood test and arranging an exercise stress test.

Q.  How is high cholesterol treated?

A.  Cholesterol-lowering medicine is needed if your total cholesterol level remains higher than 5mmol/l and you already have cardiovascular disease.Statins (eg simvastatin, atorvastatin, rosuvastatin) are the most effective medicines for lowering cholesterol. Although statins are normally very effective, there are many side effects! 

For the side effects of statins, there are two main target organs: 

1) Liver: statins directly affect the processes of cholesterol synthesis in the liver. A small number of people experience liver dysfunction as a side effect of statin therapy. 

2) Muscles: pain, aching or weakness in the muscles is very common side effects of statins. In more severe cases, especially during simultaneous treatment with certain other drugs (gemofibrozil, niacin), there may be severe, dangerous and intractable muscle damage – rhabdomyolysis. The cause of this side effect is not yet known thoroughly. However, it is assumed that, since statins act on liver enzymes, they can also affect muscle enzymes responsible for their growth. It is this property of statins that may cause pain in the muscles.

Other side effects of statins

• Depression and irritability sleep disturbances, fatigue, headaches
• Memory and attention disorders
• Pain in the joints and peripheral neuropathy

Q.Why is SMART CHOLES-DOWN so different?

A.SMART CHOLES-DOWN’s main ingredient, Citrus Bergamot, has statin like principles.[Source: Journal of Natural Products 2009]However, Citrus Bergamot lowers your cholesterol naturally with no statin side effects! The safety is based on performing all the major safety and toxicology studies, including 4 week and 13-week single and multi oral dose tests, as well as genetic toxicology studies and overdose (LD-50) tests. 

Citrus Bergamot works by blocking a key enzyme in the production of cholesterol and inhibits the HMG-CoA (3-hydroxy-3-methyglutaryl COA) reductase, an enzyme linked to the liver’s cholesterol production, thus inhibitingthe liver’s ability to produce LDL.Citrus Bergamot also has the highest content of flavanoids in the citrus family of fruits. Flavanoids are plant nutrients found in flowers, rinds, leaves, and fruits. Many of those flavanoids have been shown to reduce cholesterol in clinical studies. Two flavanoids; brutelidine and melitidine, as well as the active compound naringin have been shown through research to significantly reduce the overall cholesterol, LDLs triglycerides, and blood glucose levels, while increasing HDLs (good cholesterol).

Q.  What are the advantages of SMART CHOLES-DOWN?

A.  Human clinical trials have shown Citrus Bergamot to lower LDL levels from 20% - 59% (Statin 18% to55%), and to raise HDL levels from 7% to 83% (Statin 5% - 15%). According to the Mayo Clinic, raisingyour HDL cholesterol level 1 milligram per deciliter (mg/dL) of blood can reduce your heart attack riskby 3 percent. In human clinical, bergamot juice raise HDL by an average of 56% while bergamotpolyphenolic extract raise HDL by an average of 43%. There are no other products that can raise HDLlike citrus bergamot!.

The inclusion of Ascorbic Acid in SMART CHOLES-DOWNdecreases risk of cardiovascular disease and strokes through a small reduction in systolic blood pressure, maximizing its therapeutic action. 

From our 238 subject human study, the results are astonishing: 

If you take 1 a day for 30 days, your HDL went up 22.9%, LDL down by 23.1%, Tryglycerides down by 29.9% and Blood glucose by 18.8%.  For those who take 2 pills a day, after 30 days, HDL went up by 40%, LDL down by 36%, Trygycerides by 38% and Blood glucose by 22%.